After almost 300 hours in this game and 1 rocket launched I finally feel like I'm past the super newbie stage and now heading into 'fully addicted slight newbie' stage.
Previously (and in my current game) I'm not considering ratios or numbers and I'm just building what feels right. For example, to build something like yellow belts I'll just chuck down 6 assem. 2 machines and let it go to work. but now I'd really like to understand the process of all the calculations.
I've seen there are sites like kirk mcdonalds ratio calculator but 1. I have no idea how to use it and 2. I'd like to work this stuff out for myself.
So my questions I guess are, how do you go about starting to calculate? What are you calculating? Are you calculating for end game?
I see lots of comments about 10 science per minute or whatever and I'm wondering how you know that? How do you calculate how many green circuits to produce at any given time?
Can someone give me a guide on how to do this? or point me in the direction of a link. I've done some popular search site searching but have so far come up with nothing that's helped.
Treat me like an idiot and tell me all you know

Because as we all know, the factory must grow.
Thanks all,
Premier2k